Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714483 | 0.91 | ABCB1 (0.54) | POLBABCB1 | |
| SCHEMBL9714633 | 0.91 | ALDH1A1 (0.56) | ABCB1 | |
| Hydrochloric Acid SCHEMBL8166856 | 0.90 | ABCB1 (0.53) | POLBABCB1 | |
| SCHEMBL9714635 | 0.90 | POLB (0.63) | POLBABCB1CYP3A4CYP2C9 | |
| SCHEMBL5058440 | 0.88 | HPGD (0.64) | ABCB1CYP3A4 | |
| Hydrochloric Acid SCHEMBL8167113 | 0.87 | HPGD (0.62) | ABCB1CYP3A4 | |
| SCHEMBL9714291 | 0.87 | ABCB1 (0.64) | POLBABCB1CYP3A4CYP2C9 | |
| SCHEMBL9714096 | 0.87 | POLB (0.56) | POLBABCB1CYP3A4CYP2C9 | |
| SCHEMBL10718344 | 0.86 | ABCB1 (0.57) | ABCB1 | |
| SCHEMBL9714340 | 0.85 | ABCB1 (0.49) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985461-A | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1991-01-15 | — | — | US | claimed |
| EP-0245950-B1 | INSECTICIDAL N-SUBSTITUTED-N' - SUBSTITUTED-N, N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1992-06-17 | — | — | EP | disclosed |
| EP-0236618-B1 | INSECTICIDAL N'-SUBSTITUTED-N,N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |
| US-4985461-A | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1991-01-15 | — | — | US | disclosed |
| US-4716046-A | IMPREGNATION WITH SUCROSE AND GUM ARABIC | DRIDRINKS N.V. (AN) | 1987-12-29 | — | — | US | disclosed |
| EP-0236618-A2 | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |