Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | PLK1 | P53350 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714140 | 0.94 | POLB (0.78) | HTTPOLBHPGDSMN1; SMN2ABCB1 | |
| SCHEMBL9714138 | 0.94 | POLB (0.78) | HTTPOLBHPGDSMN1; SMN2ABCB1 | |
| SCHEMBL10719281 | 0.89 | ABCB1 (0.76) | HTTPOLBABCB1CYP3A4CYP2C9 | |
| SCHEMBL5064138 | 0.88 | ABCB1 (0.57) | HTTPOLBHPGDSMN1; SMN2ABCB1 | |
| SCHEMBL9496366 | 0.87 | HTT (0.56) | HTTPOLBHPGDSMN1; SMN2ABCB1 | |
| SCHEMBL10719128 | 0.86 | ABCB1 (0.71) | HTTPOLBSMN1; SMN2ABCB1CYP3A4 | |
| SCHEMBL10721630 | 0.83 | HTT (0.61) | HTTABCB1 | |
| SCHEMBL9824845 | 0.82 | POLB (0.78) | HTTPOLBHPGDSMN1; SMN2ABCB1 | |
| SCHEMBL9824849 | 0.82 | POLB (0.78) | HTTPOLBHPGDSMN1; SMN2ABCB1 | |
| SCHEMBL9714422 | 0.82 | POLB (0.73) | POLBHPGDSMN1; SMN2ABCB1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0245950-B1 | INSECTICIDAL N-SUBSTITUTED-N' - SUBSTITUTED-N, N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1992-06-17 | — | — | EP | disclosed |
| EP-0236618-B1 | INSECTICIDAL N'-SUBSTITUTED-N,N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |
| US-4985461-A | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1991-01-15 | — | — | US | disclosed |
| EP-0236618-A2 | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |