Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9824845 | 1.00 | POLB (0.78) | POLBCYP3A4CYP2C9HTTHPGD | |
| SCHEMBL10720254 | 0.93 | POLB (0.68) | POLBCYP3A4CYP2C9HTTHPGD | |
| SCHEMBL9714140 | 0.89 | POLB (0.78) | POLBCYP3A4CYP2C9HTTHPGD | |
| SCHEMBL9714138 | 0.89 | POLB (0.78) | POLBCYP3A4CYP2C9HTTHPGD | |
| Rh-5849 SCHEMBL1538531 | 0.88 | POLB (1.00) | POLBCYP3A4CYP2C9HPGDSMN1; SMN2 | |
| SCHEMBL8167374 | 0.85 | POLB (0.88) | POLBCYP3A4CYP2C9HPGDSMN1; SMN2 | |
| SCHEMBL10718795 | 0.85 | POLB (0.72) | POLBCYP3A4CYP2C9HTTHPGD | |
| SCHEMBL10719027 | 0.85 | POLB (0.72) | POLBCYP3A4CYP2C9HTTHPGD | |
| SCHEMBL10718612 | 0.85 | POLB (0.72) | POLBCYP3A4CYP2C9HTTHPGD | |
| SCHEMBL9825975 | 0.84 | POLB (0.80) | POLBCYP3A4CYP2C9HTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236618-B1 | INSECTICIDAL N'-SUBSTITUTED-N,N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |
| US-4985461-A | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1991-01-15 | — | — | US | disclosed |
| EP-0236618-A2 | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |