SCHEMBL9714726

SCHEMBL9714726

C=COC(=O)c1ccccc1O.C=COC(C)=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.53
TSHR P16473 2/20 0.53
HPGD P15428 7/20 0.46
HSD17B10 Q99714 4/20 0.46
ALOX15 P16050 2/20 0.46
TDP1 Q9NUW8 2/20 0.45
ALDH1A1 P00352 6/20 0.42
KDM4E B2RXH2 5/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
HMGB1 P09429 1/20 0.41
CA4 P22748 1/20 0.41
CA6 P23280 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
NAPRT Q6XQN6 1/20 0.41
CA14 Q9ULX7 1/20 0.41
CYP3A4 P08684 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL194863 0.91 TSHR (0.57) LMNATSHRHPGDHSD17B10ALOX15
SCHEMBL5535925 0.83 ALDH1A1 (0.47) LMNATSHRHPGDHSD17B10ALOX15
Catechol SCHEMBL27961386 0.82 LMNA (0.39) LMNATSHRHPGDHSD17B10ALOX15
SCHEMBL11727113 0.82 ESR1 (0.49) LMNATSHRHPGDHSD17B10ALOX15
SCHEMBL4372406 0.81 ALDH1A1 (0.44) LMNATSHRHPGDHSD17B10ALOX15
Acetic Acid SCHEMBL27451410 0.80 CYP3A4 (0.48) LMNATSHRHPGDHSD17B10ALOX15
SCHEMBL15175 0.80 CYP3A4 (0.55) LMNATSHRHSD17B10ALOX15TDP1
SCHEMBL7588193 0.80 TDP1 (0.45) LMNATSHRHPGDHSD17B10ALOX15
SCHEMBL28113689 0.79 CYP3A4 (0.44) LMNATSHRHPGDHSD17B10TDP1
SCHEMBL27446052 0.79 CYP3A4 (0.44) LMNATSHRHPGDHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0513331-A1 AZEOTROPIC ASSISTED TRANSVINYLATION TECHNOLOGY UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1992-11-19 EP disclosed
WO-1992009554-A1 AZEOTROPIC ASSISTED TRANSVINYLATION TECHNOLOGY UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1992-06-11 WO disclosed