Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 3/20 | 0.34 |
| ▸ | CES1 | P23141 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714880 | 1.00 | GSK3B (0.41) | GSK3BPOLBMAPTCYP1A2CYP2C19 | |
| SCHEMBL9714886 | 0.87 | GSK3B (0.42) | GSK3BPOLBMAPTCYP1A2CYP2C19 | |
| SCHEMBL9714887 | 0.87 | GSK3B (0.42) | GSK3BPOLBMAPTCYP1A2CYP2C19 | |
| SCHEMBL9714878 | 0.84 | POLB (0.41) | POLBMAPTCYP1A2CYP2C19HPGD | |
| SCHEMBL9714881 | 0.84 | POLB (0.41) | POLBMAPTCYP1A2CYP2C19HPGD | |
| SCHEMBL11472847 | 0.76 | POLB (0.36) | POLBMAPTHDAC3HDAC1HDAC2 | |
| SCHEMBL9774662 | 0.75 | PTPN1 (0.41) | GSK3BMAPTCYP1A2CYP2C19HPGD | |
| SCHEMBL9774667 | 0.75 | PTPN1 (0.41) | GSK3BMAPTCYP1A2CYP2C19HPGD | |
| SCHEMBL11068444 | 0.74 | PTGS2 (0.40) | POLBHDAC1TRPA1HTTMAPK1 | |
| SCHEMBL11063245 | 0.72 | SMN1; SMN2 (0.43) | MAPTCYP1A2CYP2C19HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0323625-B1 | Process for preparing 3-[2-chloro-2(4-chlorophenyl)-vinyl]-2,2-dimethyl-cyclopropane carboxylic acid | BAYER AG (DE) | 1992-09-09 | — | — | EP | claimed |
| US-4897505-A | Process for the preparation of 3-(2-chloro-2-(4-chloro-phenyl)-vinyl)-2,2-dimethylcyclopropanecarboxylic acid | BAYER AKTIENGESELLSCHAFT (DE) | 1990-01-30 | — | — | US | claimed |
| EP-0323625-A2 | Process for preparing 3-[2-chloro-2(4-chlorophenyl)-vinyl]-2,2-dimethyl-cyclopropane carboxylic acid | BAYER AG (DE) | 1989-07-12 | — | — | EP | claimed |
| JP-1203350-A | — | — | None | — | — | JP | disclosed |
| EP-0323625-B1 | Process for preparing 3-[2-chloro-2(4-chlorophenyl)-vinyl]-2,2-dimethyl-cyclopropane carboxylic acid | BAYER AG (DE) | 1992-09-09 | — | — | EP | disclosed |
| US-4897505-A | Process for the preparation of 3-(2-chloro-2-(4-chloro-phenyl)-vinyl)-2,2-dimethylcyclopropanecarboxylic acid | BAYER AKTIENGESELLSCHAFT (DE) | 1990-01-30 | — | — | US | disclosed |
| US-4897505-A | Process for the preparation of 3-(2-chloro-2-(4-chloro-phenyl)-vinyl)-2,2-dimethylcyclopropanecarboxylic acid | BAYER AKTIENGESELLSCHAFT (DE) | 1990-01-30 | — | — | US | disclosed |
| JP-H01203350-A | PREPARATION OF 3-(2-CHLORO-2-(4-CHLOROPHENYL)-VINYL)-2,2-DIMETHYLCYCLOPROPANECARBOXYLIC ACID | BAYER AG | 1989-08-16 | — | — | JP | disclosed |
| EP-0323625-A2 | Process for preparing 3-[2-chloro-2(4-chlorophenyl)-vinyl]-2,2-dimethyl-cyclopropane carboxylic acid | BAYER AG (DE) | 1989-07-12 | — | — | EP | disclosed |