⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL790520 | 0.97 | ALDH1A1 (0.30) | — | |
| Alcohol SCHEMBL27721062 | 0.93 | ALDH1A1 (0.33) | — | |
| SCHEMBL6553251 | 0.90 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL26921069 | 0.89 | — | — | |
| SCHEMBL30915507 | 0.89 | — | — | |
| SCHEMBL11948899 | 0.89 | — | — | |
| SCHEMBL27167199 | 0.89 | — | — | |
| SCHEMBL10005276 | 0.89 | — | — | |
| SCHEMBL21460515 | 0.88 | LMNA (0.36) | — | |
| Acetic Acid SCHEMBL16756244 | 0.87 | CAMK2A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0202594-B1 | HYDROPHILIC SILICONE RUBBER MOULDINGS AND PROCESS FOR PREPARING THESE | CIBA-GEIGY AG (CH) | 1992-08-05 | — | — | EP | claimed |
| US-4920184-A | Surface treatment with organosiloxane | CIBA-GEIGY CORPORATION (US) | 1990-04-24 | — | — | US | claimed |
| EP-0205888-B1 | MODIFIED SILICONE RUBBER, ITS USE IN LENSES AND LENSES PRODUCED WITH THIS MATERIAL | CIBA-GEIGY AG (CH) | 1989-11-23 | — | — | EP | claimed |
| US-4853453-A | Modified silicone rubber and its use as a material for optical lenses and optical lenses made from this material | CIBA-GEIGY CORPORATION (US) | 1989-08-01 | — | — | US | claimed |
| EP-0202594-A2 | Hydrophilic silicone rubber mouldings and process for preparing these | CIBA-GEIGY AG (CH) | 1986-11-26 | — | — | EP | claimed |
| EP-0202594-B1 | HYDROPHILIC SILICONE RUBBER MOULDINGS AND PROCESS FOR PREPARING THESE | CIBA-GEIGY AG (CH) | 1992-08-05 | — | — | EP | disclosed |
| EP-0205888-B1 | MODIFIED SILICONE RUBBER, ITS USE IN LENSES AND LENSES PRODUCED WITH THIS MATERIAL | CIBA-GEIGY AG (CH) | 1989-11-23 | — | — | EP | disclosed |
| US-4853453-A | Modified silicone rubber and its use as a material for optical lenses and optical lenses made from this material | CIBA-GEIGY CORPORATION (US) | 1989-08-01 | — | — | US | disclosed |