SCHEMBL9715100

SCHEMBL9715100

CC(C)(C)COC(=O)C(F)=C(F)F

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15854408 0.81 MAPK1 (0.34)
SCHEMBL2230548 0.80 CYP2C19 (0.39) CYP2C19KMT2A
SCHEMBL16768588 0.78 THRB (0.37)
SCHEMBL7699054 0.78 CYP2C19 (0.35) CYP2C19KMT2A
SCHEMBL15854402 0.76 ALDH1A1 (0.45)
SCHEMBL16768583 0.76 MAPK1 (0.31)
SCHEMBL14535446 0.75
SCHEMBL396824 0.74 TSHR (0.50) CYP2C19KMT2A
SCHEMBL899312 0.74 CYP2C19 (0.32) CYP2C19KMT2A
SCHEMBL7790725 0.74 CYP2C19 (0.32) CYP2C19KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0242080-B1 COPOLYMER COMPOSITIONS PARAGON OPTICAL INC (US) 1992-12-16 EP claimed
US-4661573-A INTRAOCULAR AND CONTACT LENSES; COPOLYMER OF PERFLUROALKYL ACRYLATE, ACRYLOXYALKYLPOLYSILOXANE, ACRYLOXYALKYLSILANOL, POLYACRYLOXYALKYLPOLYSILOXANE PARAGON OPTICAL INC. (US) 1987-04-28 US claimed