Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MC5R | P33032 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.30 |
| ▸ | ERN1 | O75460 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31347600 | 1.00 | SLC9A1 (0.42) | SLC9A1MEN1KMT2AAKR1B1BACE1 | |
| SCHEMBL27991297 | 0.84 | XDH (0.42) | SLC9A1MEN1KMT2AAKR1B1BACE1 | |
| SCHEMBL15352105 | 0.81 | SLC9A1 (0.44) | SLC9A1MEN1KMT2AAKR1B1BACE1 | |
| SCHEMBL4703026 | 0.79 | SLC9A1 (0.41) | SLC9A1MEN1KMT2AAKR1B1BACE1 | |
| SCHEMBL11738780 | 0.79 | CYP1A2 (0.53) | AKR1B1MAPK1MC5RPLAU | |
| SCHEMBL11737047 | 0.79 | AKR1B1 (0.34) | MEN1KMT2AAKR1B1MAPK1MC5R | |
| SCHEMBL11741679 | 0.79 | CYP1A2 (0.45) | MEN1KMT2AAKR1B1MAPK1MC5R | |
| SCHEMBL8732557 | 0.78 | SLC9A1 (0.41) | SLC9A1MEN1KMT2AAKR1B1BACE1 | |
| SCHEMBL7221961 | 0.78 | SLC9A1 (0.44) | SLC9A1MEN1KMT2AAKR1B1BACE1 | |
| SCHEMBL31459979 | 0.78 | SLC9A1 (0.44) | SLC9A1MEN1KMT2AAKR1B1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0143593-B1 | PESTICIDES | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1992-01-02 | — | — | EP | disclosed |
| US-4736065-A | Pesticides | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1988-04-05 | — | — | US | disclosed |
| EP-0143593-A2 | Pesticides | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1985-06-05 | — | — | EP | disclosed |