SCHEMBL9715153

SCHEMBL9715153

O=[PH](OCOS(=O)(=O)c1c(Cl)cccc1Cl)OCOS(=O)(=O)c1c(Cl)cccc1Cl

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
GAA P10253 1/20 0.31
POLB P06746 1/20 0.31
AKR1B1 P15121 1/20 0.31
CXCR2 P25025 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9715139 0.89 SLC40A1 (0.35) KMT2AALDH1A1
SCHEMBL8854423 0.87 KMT2A (0.33) KMT2AGAAPOLBAKR1B1CXCR2
SCHEMBL27548401 0.85 CYP1A2 (0.31) ALDH1A1
SCHEMBL27468776 0.83
SCHEMBL8730032 0.82
SCHEMBL27468777 0.81 F2 (0.36) ALDH1A1GAA
SCHEMBL8854564 0.77 SLC40A1 (0.34) KMT2AALDH1A1
SCHEMBL8764729 0.77 KMT2A (0.32) KMT2AMEN1ALDH1A1TDP1GAA
SCHEMBL8731854 0.76 KMT2A (0.34) KMT2AMEN1ALDH1A1TDP1GAA
SCHEMBL8854619 0.76 KMT2A (0.31) KMT2AMEN1ALDH1A1TDP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1133120-A Combination containing phosphine sulfonate ester herbicide and dichloro acetamide safety agent ROHM & HAAS (US) 1996-10-16 CN claimed
EP-0511826-A2 Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1992-11-04 EP claimed