SCHEMBL8764729

SCHEMBL8764729

O=[PH](Cl)COS(=O)(=O)c1c(Cl)cccc1Cl

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
GAA P10253 1/20 0.32
POLB P06746 1/20 0.32
AKR1B1 P15121 1/20 0.32
CXCR2 P25025 1/20 0.31
ATM Q13315 1/20 0.30
DAGLA Q9Y4D2 1/20 0.30
IDO1 P14902 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
NSD2 O96028 1/20 0.30
BCHE P06276 1/20 0.30
DAO P14920 1/20 0.30
CES1 P23141 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8764019 0.89 SLC40A1 (0.36) KMT2AALDH1A1ATM
SCHEMBL8731854 0.84 KMT2A (0.34) KMT2AMEN1ALDH1A1TDP1GAA
SCHEMBL9715153 0.77 KMT2A (0.31) KMT2AMEN1ALDH1A1TDP1GAA
SCHEMBL8854423 0.75 KMT2A (0.33) KMT2AGAAPOLBAKR1B1CXCR2
SCHEMBL8734771 0.74 SLC40A1 (0.35) KMT2AALDH1A1GAAPOLBATM
SCHEMBL27288328 0.72 PNMT (0.42) IDO1
SCHEMBL8735700 0.71 CXCL8 (0.33)
SCHEMBL8764723 0.71 SMN1; SMN2 (0.35) KMT2AMEN1ALDH1A1TDP1GAA
SCHEMBL8734735 0.70 SMN1; SMN2 (0.46) KMT2AGAAPOLBCXCR2ATM
SCHEMBL8854619 0.70 KMT2A (0.31) KMT2AMEN1ALDH1A1TDP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0511826-B1 Phosphosulfonate herbicides ROHM & HAAS (US) 1997-07-16 EP disclosed
US-5500405-A Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1996-03-19 US disclosed
US-5272128-A Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1993-12-21 US disclosed
EP-0511826-A2 Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1992-11-04 EP disclosed