SCHEMBL9715209

SCHEMBL9715209

CC1(C=O)C=CC(c2ccccc2)C=C1

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 4/20 0.34
MAOA P21397 4/20 0.34
MAOB P27338 4/20 0.34
CACNA1B Q00975 1/20 0.33
APBA1 Q02410 1/20 0.33
CHRNA7 P36544 1/20 0.31
DDB1 Q16531 1/20 0.30
CRBN Q96SW2 1/20 0.30
TSHR P16473 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11825248 0.81 KDM1A (0.34) KDM1AMAOAMAOBCHRNA7
SCHEMBL11785556 0.80 ALDH1A1 (0.31)
SCHEMBL7511837 0.77 KDM1A (0.40) KDM1AMAOAMAOBCHRNA7TSHR
SCHEMBL8582650 0.77
SCHEMBL2558615 0.77 POLB (0.30)
SCHEMBL7427186 0.75 KDM1A (0.39) KDM1AMAOAMAOBCHRNA7TSHR
SCHEMBL20520014 0.74 EDNRA (0.32)
SCHEMBL7077759 0.74 KDM1A (0.38) KDM1AMAOAMAOBCHRNA7
SCHEMBL7199456 0.74 CHRNA7 (0.41) KDM1AMAOAMAOBCHRNA7KMT2A
SCHEMBL4371618 0.73 SLC9A1 (0.36) KDM1AMAOAMAOBCHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0502202-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-09-09 EP disclosed