Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15647555 | 0.76 | ALDH1A1 (0.40) | GAAALDH1A1CYP3A4CYP2C9TSHR | |
| SCHEMBL20205762 | 0.73 | ALDH1A1 (0.34) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL465241 | 0.73 | GAA (0.32) | GAA | |
| SCHEMBL22504293 | 0.73 | PTPN1 (0.36) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL7583136 | 0.73 | PTPN1 (0.36) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL30589484 | 0.73 | — | — | |
| SCHEMBL4385624 | 0.73 | PTPN1 (0.33) | PTPN1 | |
| SCHEMBL5926597 | 0.72 | ALDH1A1 (0.30) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL5926857 | 0.72 | ALDH1A1 (0.30) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL9883158 | 0.72 | ALDH1A1 (0.35) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101310716-A | Therapeutic agent | TAKARA BIO INC (JP) | 2008-11-26 | — | — | CN | claimed |
| CN-1791392-A | Therapeutic agents | TAKARA BIO INC (JP) | 2006-06-21 | — | — | CN | claimed |
| JP-4368352-A | — | — | None | — | — | JP | disclosed |
| CN-101310716-A | Therapeutic agent | TAKARA BIO INC (JP) | 2008-11-26 | — | — | CN | disclosed |
| CN-100415218-C | Therapeutic agents | TAKARA BIO INC (JP) | 2008-09-03 | — | — | CN | disclosed |
| CN-1791392-A | Therapeutic agents | TAKARA BIO INC (JP) | 2006-06-21 | — | — | CN | disclosed |
| JP-H04368352-A | DECALIN KETONE, METHOD FOR IMPARTING, IMPROVING, INCREASING OR REFORMING OF ODOROUS PROPERTIES OF PERFUMING COMPOSITION OR PERFUMED ARTICLES, AND PREPARATION OF PERFUMING COMPOSITION, PERFUMED ARTICLES AND DECALIN KETONE | FIRMENICH SA | 1992-12-21 | — | — | JP | disclosed |