Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15874511 | 1.00 | ALDH1A1 (0.35) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| Alcohol SCHEMBL5073410 | 0.93 | ALDH1A1 (0.35) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL9609157 | 0.73 | ALDH1A1 (0.34) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL8534893 | 0.73 | ALDH1A1 (0.34) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL9609159 | 0.73 | ALDH1A1 (0.34) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL9609158 | 0.72 | ALDH1A1 (0.33) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL30885181 | 0.72 | ALDH1A1 (0.33) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL9715210 | 0.72 | GAA (0.36) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL113255 | 0.71 | CYP3A4 (0.40) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL584183 | 0.71 | CYP1A2 (0.35) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120129925-A1 | SHIP 1 MODULATORS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2012-05-24 | — | — | US | disclosed |
| US-20080090909-A1 | negative regulator of cell growth factor receptor; pelorol (benzo(a)fluorene) related compounds from marine sponge species; antiinflammatory, antitumor agent, immunostimulant; control gene expression, differentiation, metabolism, phospholipid signaling pathway, signal tansduction | THE UNIVERSITY OF BRITISH COLUMBIA | 2008-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080090909-A1 | negative regulator of cell growth factor receptor; pelorol (benzo(a)fluorene) related compounds from marine sponge species; antiinflammatory, antitumor agent, immunostimulant; control gene expression, differentiation, metabolism, phospholipid signaling pathway, signal tansduction | STAT1, STING1, IRF3 | ALDH1A1 2237/4885CYP3A4 4744/4885CYP2C9 4641/4885 |
| US-20120129925-A1 | SHIP 1 MODULATORS | PPP1R10, SACM1L, PPP1R1B | ALDH1A1 1182/4885CYP3A4 2887/4885CYP2C9 3589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.