Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 6/20 | 0.62 |
| ▸ | QDPR | P09417 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14560140 | 0.91 | ESR2 (0.54) | ESR2QDPRDRD2DRD3DRD4 | |
| SCHEMBL14560139 | 0.85 | ESR2 (0.49) | ESR2QDPRDRD2DRD3DRD4 | |
| SCHEMBL9715313 | 0.82 | ESR2 (0.61) | ESR2QDPRDRD2DRD3DRD4 | |
| SCHEMBL10930951 | 0.80 | ESR2 (0.59) | ESR2QDPRDRD2DRD3DRD4 | |
| SCHEMBL2721633 | 0.79 | ESR2 (0.57) | ESR2QDPRESR1KDM1ACYP3A4 | |
| SCHEMBL10932344 | 0.79 | ESR2 (0.57) | ESR2QDPRDRD2DRD3DRD4 | |
| SCHEMBL20524227 | 0.77 | ESR2 (1.00) | ESR2QDPRDRD2DRD3DRD4 | |
| SCHEMBL9248162 | 0.77 | ESR2 (0.56) | ESR2QDPRDRD2DRD3DRD4 | |
| SCHEMBL503467 | 0.77 | ESR2 (0.41) | ESR2QDPRESR1TP53CYP3A4 | |
| SCHEMBL8102077 | 0.76 | ESR2 (0.54) | ESR2QDPRDRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7196232-B2 | 4,4′-dihydroxyphenyl bicyclohexenes | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-03-27 | — | — | US | claimed |
| US-20060129001-A1 | Novel 4,4'-dihydroxyphenyl bicyclohexenes | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2006-06-15 | — | — | US | claimed |
| US-9310681-B2 | Negative resist composition and patterning process using same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2016-04-12 | — | — | US | disclosed |
| US-9310681-B2 | Negative resist composition and patterning process using same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2016-04-12 | — | — | US | disclosed |
| US-20150198883-A1 | NEGATIVE RESIST COMPOSITION AND PATTERNING PROCESS USING SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2015-07-16 | — | — | US | disclosed |
| US-20150198883-A1 | NEGATIVE RESIST COMPOSITION AND PATTERNING PROCESS USING SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2015-07-16 | — | — | US | disclosed |
| EP-2383265-B1 | METHOD FOR MANUFACTURING TRIMELLITIC ANHYDRIDE ARYL ESTER | HONSHU CHEMICAL IND (JP) | 2015-03-11 | — | — | EP | disclosed |
| US-8563751-B2 | Method for manufacturing trimellitic anhydride aryl ester | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2013-10-22 | — | — | US | disclosed |
| US-20120029215-A1 | METHOD FOR MANUFACTURING TRIMELLITIC ANHYDRIDE ARYL ESTER | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-02-02 | — | — | US | disclosed |
| EP-2383265-A1 | METHOD FOR MANUFACTURING TRIMELLITIC ANHYDRIDE ARYL ESTER | Honshu Chemical Industry Co., Ltd. (JP) | 2011-11-02 | — | — | EP | disclosed |
| US-7196232-B2 | 4,4′-dihydroxyphenyl bicyclohexenes | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-03-27 | — | — | US | disclosed |
| US-7196232-B2 | 4,4′-dihydroxyphenyl bicyclohexenes | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-03-27 | — | — | US | disclosed |
| US-20060129001-A1 | Novel 4,4'-dihydroxyphenyl bicyclohexenes | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120029215-A1 | METHOD FOR MANUFACTURING TRIMELLITIC ANHYDRIDE ARYL ESTER | TRIM4, CA6, TRIM58 | ESR2 4574/4885QDPR 3754/4885DRD2 4203/4885 |
| US-20060129001-A1 | Novel 4,4'-dihydroxyphenyl bicyclohexenes | DBF4, DCUN1D4, SDC4 | ESR2 2548/4885QDPR 885/4885DRD2 108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.