SCHEMBL9715384

SCHEMBL9715384

C=C(C)C(=O)Nc1nccs1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.61
RAB9A P51151 6/20 0.57
NPC1 O15118 5/20 0.57
PPARG P37231 1/20 0.57
NCOR2 Q9Y618 1/20 0.57
ALDH1A1 P00352 1/20 0.57
PKM P14618 1/20 0.57
SMN1; SMN2 Q16637 5/20 0.55
STAT1 P42224 1/20 0.55
AGER Q15109 1/20 0.53
KMT2A Q03164 3/20 0.51
MEN1 O00255 2/20 0.51
ACP1 P24666 1/20 0.51
MAPT P10636 1/20 0.51
KDM4E B2RXH2 1/20 0.51
LMNA P02545 3/20 0.50
HPGD P15428 2/20 0.50
NLRP1 Q9C000 1/20 0.50
METAP2 P50579 1/20 0.50
METAP1 P53582 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9425207 0.89 SMN1; SMN2 (0.54) HTTRAB9ANPC1PPARGNCOR2
SCHEMBL115951 0.82
SCHEMBL13075600 0.82
Hydrochloric Acid SCHEMBL29059238 0.81 AGER (0.64) HTTRAB9ANPC1PPARGNCOR2
Hydrochloric Acid SCHEMBL28995499 0.81 AGER (0.64) HTTRAB9ANPC1PPARGNCOR2
SCHEMBL208500 0.80 L3MBTL1 (0.55) HTTRAB9ANPC1PPARGNCOR2
SCHEMBL15293582 0.79 KDM4E (0.52) HTTALDH1A1SMN1; SMN2AGERKMT2A
SCHEMBL9212252 0.79 HTT (0.62) HTTRAB9ANPC1ALDH1A1PKM
SCHEMBL7829112 0.79
SCHEMBL10031568 0.78 KMT2A (0.77) ALDH1A1PKMSMN1; SMN2KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0164807-B1 MULTIFUNCTIONAL ADDITIVE FOR LUBRIFICATING OILS AND PROCESS FOR THE PREPARATION THEREOF AGIP PETROLI S.p.A. (IT) 1989-10-18 EP claimed
US-4618439-A GRAFT POLYMER OF ACRYLIC ESTER AGIP PETROLI S.P.A. (IT) 1986-10-21 US claimed
EP-0164807-A2 Multifunctional additive for lubrificating oils and process for the preparation thereof AGIP PETROLI S.p.A. (IT) 1985-12-18 EP claimed
US-11285458-B2 Separating agent NATIONAL UNIVERSITY CORPORATION KYOTO INSTITUTE OF TECHNOLOGY (JP) 2022-03-29 US disclosed
EP-3021114-B1 SEPARATING AGENT NAT UNIV CORP KYOTO INST TECHNOLOGY (JP) 2021-03-03 EP disclosed
EP-3021114-B1 SEPARATING AGENT NAT UNIV CORP KYOTO INST TECHNOLOGY (JP) 2021-03-03 EP disclosed
US-20160168302-A1 SEPARATING AGENT NATIONAL UNIVERSITY CORPORATION KYOTO INSTITUTE OF TECHNOLOGY (JP) 2016-06-16 US disclosed
US-20160168302-A1 SEPARATING AGENT NATIONAL UNIVERSITY CORPORATION KYOTO INSTITUTE OF TECHNOLOGY (JP) 2016-06-16 US disclosed
EP-3021114-A1 SEPARATING AGENT National University Corporation Kyoto Institute of Technology (JP) 2016-05-18 EP disclosed
WO-2015005361-A1 SEPARATING AGENT 国立大学法人京都工芸繊維大学 (JP) 2015-01-15 WO disclosed
US-8389736-B2 Compounds having activity in correcting mutant-CFTR processing and uses thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2013-03-05 US disclosed
EP-0262502-B1 COMPATIBLE MIXTURES FROM POLYCARBONATE AND METHYLMETHACRYLATE COPOLYMERS RÖHM GMBH (DE) 1992-01-02 EP disclosed
EP-0164807-B1 MULTIFUNCTIONAL ADDITIVE FOR LUBRIFICATING OILS AND PROCESS FOR THE PREPARATION THEREOF AGIP PETROLI S.p.A. (IT) 1989-10-18 EP disclosed
US-4749749-A TRANSPARENT THERMOPLASTIC BLEND; RING-SUBSTITUTED (METH)ACRYLAMIDE MONOMERS ROHM GMBH CHEMISCHE FABRIK (DE) 1988-06-07 US disclosed
EP-0262502-A2 Compatible mixtures from polycarbonate and methylmethacrylate copolymers Röhm GmbH (DE) 1988-04-06 EP disclosed
US-4618439-A GRAFT POLYMER OF ACRYLIC ESTER AGIP PETROLI S.P.A. (IT) 1986-10-21 US disclosed
EP-0164807-A2 Multifunctional additive for lubrificating oils and process for the preparation thereof AGIP PETROLI S.p.A. (IT) 1985-12-18 EP disclosed