Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | QPCT | Q16769 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1464358 | 0.86 | ALDH1A1 (0.57) | ALDH1A1CYP19A1CYP11B1CYP11B2QPCT | |
| SCHEMBL11006626 | 0.78 | ALDH1A1 (0.52) | ALDH1A1CYP19A1CYP11B1CYP11B2QPCT | |
| SCHEMBL20377953 | 0.77 | VDR (0.46) | ALDH1A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11263948 | 0.76 | ALDH1A1 (0.47) | ALDH1A1CYP19A1CYP11B1CYP11B2QPCT | |
| SCHEMBL28571205 | 0.76 | ALDH1A1 (0.59) | ALDH1A1CYP19A1CYP11B1CYP11B2QPCT | |
| SCHEMBL2455924 | 0.73 | ALDH1A1 (0.53) | ALDH1A1CYP19A1CYP11B1CYP11B2QPCT | |
| SCHEMBL4952812 | 0.71 | ALDH1A1 (0.57) | ALDH1A1CYP19A1CYP11B1CYP11B2QPCT | |
| SCHEMBL21806876 | 0.71 | VDR (0.38) | ALDH1A1CTDSP1 | |
| SCHEMBL19975463 | 0.71 | ALDH1A1 (0.39) | ALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL28075752 | 0.71 | ALDH1A1 (0.46) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0275821-B1 | SUBSTITUTED ALKANEDIPHOSPHONIC ACIDS | CIBA-GEIGY AG (CH) | 1992-02-26 | — | — | EP | disclosed |
| US-4939130-A | Substituted alkanediphosphonic acids and pharmaceutical use | CIBA-GEIGY CORPORATION (US) | 1990-07-03 | — | — | US | disclosed |
| EP-0275821-A1 | Substituted alkanediphosphonic acids | CIBA-GEIGY AG (CH) | 1988-07-27 | — | — | EP | disclosed |