Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1799910 | 0.89 | TSHR (0.44) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL284885 | 0.89 | TSHR (0.50) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL284174 | 0.86 | TSHR (0.54) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL284797 | 0.84 | TSHR (0.42) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL4113049 | 0.83 | TSHR (0.40) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL5537440 | 0.81 | TSHR (0.59) | TSHRALDH1A1CYP3A4HPGDATM | |
| SCHEMBL5792196 | 0.79 | TSHR (0.47) | TSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL1603365 | 0.79 | TSHR (0.52) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL9132116 | 0.78 | TSHR (0.33) | TSHRALDH1A1CYP3A4HPGDATM | |
| SCHEMBL10519867 | 0.78 | NAAA (0.52) | TSHRALDH1A1CYP3A4HPGDATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992009639-A2 | SURFACE-ACTIVE MACROMONOMERS | BAUSCH & LOMB INCORPORATED (US) | 1992-06-11 | — | — | WO | disclosed |