Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4793090 | 0.82 | SMN1; SMN2 (0.53) | MEN1KMT2ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL23161511 | 0.80 | SMN1; SMN2 (0.56) | MEN1KMT2ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL3042980 | 0.80 | ALDH1A1 (0.56) | MEN1KMT2ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL30851436 | 0.78 | KEAP1 (0.57) | MEN1KMT2ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL1239113 | 0.78 | KEAP1 (0.57) | MEN1KMT2ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL7611671 | 0.78 | ALDH1A1 (0.57) | MEN1KMT2ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL6005480 | 0.78 | KEAP1 (0.57) | MEN1KMT2ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL4072195 | 0.78 | SMN1; SMN2 (0.46) | MEN1KMT2ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL1267622 | 0.77 | SMN1; SMN2 (0.53) | MEN1KMT2ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL4069218 | 0.75 | SMN1; SMN2 (0.44) | MEN1KMT2ASMN1; SMN2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308961-B1 | THIADIAZINES, PROCESS FOR PRODUCTION THEREOF, AND INSECTICIDE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-07-08 | — | — | EP | disclosed |
| US-5021412-A | Protecting agricultural crops | MITSUI TOATSU CHEMICALS, INC. (JP) | 1991-06-04 | — | — | US | disclosed |
| EP-0308961-A1 | Thiadiazines, process for production thereof, and insecticide | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-03-29 | — | — | EP | disclosed |