Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | MGLL | Q99685 | 3/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | EBP | Q15125 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11252860 | 0.75 | GBA1 (0.48) | GBA1PTGS1PTGS2MGLLFAAH | |
| SCHEMBL5858708 | 0.73 | MGLL (0.41) | GBA1PTGS1PTGS2MGLLFAAH | |
| SCHEMBL11266226 | 0.72 | GBA1 (0.46) | GBA1PTGS1PTGS2MGLLFAAH | |
| SCHEMBL11266229 | 0.72 | GBA1 (0.46) | GBA1PTGS1PTGS2MGLLFAAH | |
| SCHEMBL28740068 | 0.72 | PIK3CD (0.51) | GBA1PTGS1PTGS2MGLLALDH1A1 | |
| SCHEMBL30697352 | 0.72 | PIK3CD (0.51) | GBA1PTGS1PTGS2MGLLALDH1A1 | |
| Bromide SCHEMBL27981325 | 0.71 | PIK3CD (0.50) | GBA1PTGS1PTGS2MGLLALDH1A1 | |
| SCHEMBL4653587 | 0.70 | PIK3CD (0.53) | GBA1ALDH1A1ALOX5 | |
| SCHEMBL17351113 | 0.69 | GBA1 (0.44) | GBA1PTGS1PTGS2MGLLFAAH | |
| SCHEMBL28354948 | 0.69 | GBA1 (0.44) | GBA1ALDH1A1ALOX5TP53HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5142044-A | Lactam derivatives | WHITBY RESEARCH, INC. (US) | 1992-08-25 | — | — | US | claimed |