SCHEMBL9715666

SCHEMBL9715666

O=C(O)C(Cc1ccccc1)NC(Cl)P(=O)(O)O

nearest known ligand 0.51

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MME P08473 2/20 0.51
L3MBTL1 Q9Y468 1/20 0.48
LAP3 P28838 3/20 0.47
ANPEP P15144 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
ACP3 P15309 1/20 0.46
PTPN1 P18031 1/20 0.46
NAALAD2 Q9Y3Q0 1/20 0.46
ECE1 P42892 1/20 0.45
MMP2 P08253 1/20 0.44
MMP9 P14780 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9245828 0.83 MME (0.52) MMEL3MBTL1LAP3ANPEPNPSR1
SCHEMBL8697148 0.83 MME (0.52) MMEL3MBTL1LAP3ANPEPNPSR1
SCHEMBL9242144 0.81 ECE1 (0.64) MMEL3MBTL1LAP3ANPEPECE1
SCHEMBL9068541 0.81 MME (0.70) MMEL3MBTL1NPSR1NAALAD2MMP2
SCHEMBL7379335 0.81 MME (0.70) MMEL3MBTL1NPSR1NAALAD2MMP2
Ammonia Solution, Strong SCHEMBL2415760 0.80 MME (0.50) MMEL3MBTL1LAP3ANPEPNPSR1
SCHEMBL3090103 0.78 MME (0.48) MMEL3MBTL1LAP3ANPEPNPSR1
SCHEMBL3090098 0.78 MME (0.48) MMEL3MBTL1LAP3ANPEPNPSR1
SCHEMBL43350 0.78 MME (0.62) MMEL3MBTL1LAP3ANPEPNPSR1
SCHEMBL43351 0.78 MME (0.62) MMEL3MBTL1LAP3ANPEPNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1994007913-A1 PEPTIDE ANTAGONISTS OF SH2 BINDING AND THERAPEUTIC USES THEREOF WARNER-LAMBERT COMPANY (US) 1994-04-14 WO disclosed