Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.80 |
| ▸ | PTPRC | P08575 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.58 |
| ▸ | ALPI | P09923 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | XIAP | P98170 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | FYN | P06241 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tyrosine SCHEMBL192542 | 0.93 | SLC7A5 (0.86) | SLC7A5PTPRCPTGS1ALPIPKM | |
| Tyrosine SCHEMBL192543 | 0.93 | SLC7A5 (0.86) | SLC7A5PTPRCPTGS1ALPIPKM | |
| Tyrosine SCHEMBL15689273 | 0.93 | SLC7A5 (0.86) | SLC7A5PTPRCPTGS1ALPIPKM | |
| Tyrosine SCHEMBL29230366 | 0.93 | SLC7A5 (0.86) | SLC7A5PTPRCPTGS1ALPIPKM | |
| Tyrosine SCHEMBL8934985 | 0.93 | SLC7A5 (0.86) | SLC7A5PTPRCPTGS1ALPIPKM | |
| Tyrosine SCHEMBL28831604 | 0.92 | SLC7A5 (0.83) | SLC7A5PTPRCPTGS1ALPIPKM | |
| Tyrosine SCHEMBL28873419 | 0.92 | SLC7A5 (0.83) | SLC7A5PTPRCPTGS1ALPIPKM | |
| Tyrosine SCHEMBL20558574 | 0.92 | SLC7A5 (0.83) | SLC7A5PTPRCPTGS1ALPIPKM | |
| Tyrosine SCHEMBL5499765 | 0.90 | SLC7A5 (0.80) | SLC7A5PTPRCPTGS1ALPIPKM | |
| Tyrosine SCHEMBL11676395 | 0.89 | SLC7A5 (1.00) | SLC7A5PTPRCPTGS1ALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994007913-A1 | PEPTIDE ANTAGONISTS OF SH2 BINDING AND THERAPEUTIC USES THEREOF | WARNER-LAMBERT COMPANY (US) | 1994-04-14 | — | — | WO | claimed |
| WO-1994007913-A1 | PEPTIDE ANTAGONISTS OF SH2 BINDING AND THERAPEUTIC USES THEREOF | WARNER-LAMBERT COMPANY (US) | 1994-04-14 | — | — | WO | disclosed |