Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | CDK4 | P11802 | 1/20 | 0.46 |
| ▸ | CCND1 | P24385 | 1/20 | 0.46 |
| ▸ | JUN | P05412 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.42 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | GUSB | P08236 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | ECE2 | P0DPD6 | 2/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21166609 | 0.74 | TRPA1 (0.52) | TRPA1NFKB1CDK4CCND1JUN | |
| SCHEMBL108389 | 0.73 | TRPA1 (0.76) | TRPA1NFKB1CDK4CCND1JUN | |
| SCHEMBL717976 | 0.73 | TRPA1 (0.76) | TRPA1NFKB1CDK4CCND1JUN | |
| SCHEMBL7174983 | 0.73 | TRPA1 (0.43) | TRPA1NFKB1CDK4CCND1JUN | |
| SCHEMBL6741729 | 0.71 | MAOB (0.44) | TRPA1NFE2L2CA1MAPTLMNA | |
| SCHEMBL7027842 | 0.70 | TRPA1 (0.58) | TRPA1NFKB1CDK4CCND1JUN | |
| SCHEMBL28268121 | 0.69 | CDK4 (0.74) | TRPA1NFKB1CDK4CCND1JUN | |
| SCHEMBL9328084 | 0.69 | TRPA1 (0.68) | TRPA1NFKB1CDK4CCND1JUN | |
| SCHEMBL15018017 | 0.69 | ABL1 (0.49) | TRPA1NFKB1CDK4CCND1JUN | |
| SCHEMBL501628 | 0.68 | TRPA1 (0.46) | TRPA1NFKB1CDK4CCND1JUN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0360128-B1 | COMPATIBLE POLYMER COMPOSITION | RÖHM GMBH (DE) | 1992-12-23 | — | — | EP | disclosed |