SCHEMBL9715710

SCHEMBL9715710

C=C(C(=C)c1ccccc1[N+](=O)[O-])c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.51
CTSD P07339 1/20 0.49
MAPT P10636 3/20 0.48
GAA P10253 2/20 0.48
HTT P42858 2/20 0.48
KDM4E B2RXH2 1/20 0.48
HPGD P15428 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
TSHR P16473 1/20 0.45
POLB P06746 1/20 0.44
MAOB P27338 1/20 0.44
LMNA P02545 1/20 0.43
CES2 O00748 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1628124 0.84 ALDH1A1 (0.58) ALDH1A1CTSDMAPTGAAHTT
SCHEMBL1628128 0.84 ALDH1A1 (0.58) ALDH1A1CTSDMAPTGAAHTT
SCHEMBL1160339 0.79 CTSD (0.57) ALDH1A1CTSDMAPTGAAHTT
Ethylene SCHEMBL28122899 0.79 ALDH1A1 (0.56) ALDH1A1CTSDMAPTGAAHTT
SCHEMBL411359 0.78 ALDH1A1 (0.59) ALDH1A1CTSDMAPTGAAHTT
SCHEMBL27637513 0.78 ALDH1A1 (0.59) ALDH1A1CTSDMAPTGAAHTT
SCHEMBL28078132 0.77 ALDH1A1 (0.54) ALDH1A1CTSDMAPTGAAHTT
SCHEMBL547216 0.77 ALDH1A1 (0.58) ALDH1A1CTSDMAPTGAAHTT
SCHEMBL114441 0.76 ALDH1A1 (0.53) ALDH1A1CTSDMAPTGAAHTT
Water SCHEMBL4951772 0.76 ALDH1A1 (0.58) ALDH1A1CTSDMAPTGAAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0304495-B1 PROCESS FOR SELECTIVELY MONOHYDROESTERIFYING DIOLEFIN NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1992-05-27 EP disclosed
US-4908473-A Reacting a (1-arylethenyl)vinylbenzene with carbon monoxide and water or alcohol in the presence of carbonylation catalyst NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1990-03-13 US disclosed
EP-0304495-A1 PROCESS FOR SELECTIVELY MONOHYDROESTERIFYING DIOLEFIN NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-03-01 EP disclosed