Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 12/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 11/20 | 0.53 |
| ▸ | LMNA | P02545 | 6/20 | 0.53 |
| ▸ | CXCR1 | P25024 | 4/20 | 0.53 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | SLC22A6 | Q4U2R8 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.53 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9715740 | 0.87 | PTGS2 (0.50) | PTGS2PTGS1LMNACXCR1CXCR2 | |
| SCHEMBL6343087 | 0.85 | PTGS2 (0.66) | PTGS2PTGS1LMNACXCR1CXCR2 | |
| SCHEMBL5313395 | 0.85 | PTGS2 (0.71) | PTGS2PTGS1LMNACXCR1CXCR2 | |
| SCHEMBL7704968 | 0.85 | PTGS2 (0.71) | PTGS2PTGS1LMNACXCR1CXCR2 | |
| SCHEMBL13974049 | 0.84 | PTGS1 (0.71) | PTGS2PTGS1LMNACXCR1CXCR2 | |
| SCHEMBL9632545 | 0.84 | PTGS1 (0.71) | PTGS2PTGS1LMNACXCR1CXCR2 | |
| SCHEMBL10415941 | 0.81 | PTGS2 (0.55) | PTGS2PTGS1LMNACXCR1CXCR2 | |
| SCHEMBL11730538 | 0.80 | PTGS2 (0.48) | PTGS2PTGS1LMNACXCR1CXCR2 | |
| SCHEMBL6547367 | 0.80 | MEN1 (0.53) | LMNAMAPTSMN1; SMN2ALDH1A1HIF1A | |
| Ethylene SCHEMBL28098281 | 0.80 | PTGS2 (0.69) | PTGS2PTGS1LMNACXCR1CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0304495-B1 | PROCESS FOR SELECTIVELY MONOHYDROESTERIFYING DIOLEFIN | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1992-05-27 | — | — | EP | disclosed |
| US-4908473-A | Reacting a (1-arylethenyl)vinylbenzene with carbon monoxide and water or alcohol in the presence of carbonylation catalyst | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1990-03-13 | — | — | US | disclosed |
| EP-0304495-A1 | PROCESS FOR SELECTIVELY MONOHYDROESTERIFYING DIOLEFIN | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1989-03-01 | — | — | EP | disclosed |