Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9715818 | 1.00 | USP2 (0.39) | USP2ALDH1A1HPGDTDP1TSHR | |
| SCHEMBL9715876 | 0.98 | ALDH1A1 (0.37) | USP2ALDH1A1HPGDTDP1TSHR | |
| SCHEMBL14956731 | 0.86 | IDH1 (0.33) | MAPTKMT2AIDH1 | |
| SCHEMBL9715864 | 0.83 | TDP1 (0.38) | USP2ALDH1A1HPGDTDP1TSHR | |
| SCHEMBL9715842 | 0.83 | TDP1 (0.38) | USP2ALDH1A1HPGDTDP1TSHR | |
| SCHEMBL9222233 | 0.81 | ALDH1A1 (0.39) | USP2ALDH1A1HPGDTDP1TSHR | |
| SCHEMBL8379586 | 0.81 | LMNA (0.35) | USP2ALDH1A1HPGDTDP1TSHR | |
| SCHEMBL9715897 | 0.81 | LMNA (0.35) | USP2ALDH1A1HPGDTDP1TSHR | |
| SCHEMBL31097221 | 0.79 | TDP1 (0.40) | USP2ALDH1A1HPGDTDP1TSHR | |
| SCHEMBL10319034 | 0.79 | KCNH2 (0.41) | ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098981-A | POLYORGANOSILOXANE | CHISSO CORPORATION (JP) | 1992-03-24 | — | — | US | disclosed |
| EP-0349920-A2 | Polyorganosiloxane | Chisso Corporation (JP) | 1990-01-10 | — | — | EP | disclosed |