Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.35 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9715900 | 0.98 | USP2 (0.40) | TDP1USP2ALDH1A1HPGDTLR8 | |
| SCHEMBL8072572 | 0.77 | TAAR1 (0.47) | TDP1USP2ALDH1A1HPGDTLR8 | |
| SCHEMBL29199586 | 0.77 | LIPG (0.53) | TDP1EP300KAT2BKAT5KAT8 | |
| SCHEMBL8071303 | 0.77 | TAAR1 (0.47) | TDP1USP2ALDH1A1HPGDTLR8 | |
| SCHEMBL8062063 | 0.77 | TAAR1 (0.47) | TDP1USP2ALDH1A1HPGDTLR8 | |
| SCHEMBL2101331 | 0.77 | LIPG (0.53) | TDP1EP300KAT2BKAT5KAT8 | |
| SCHEMBL29199609 | 0.77 | LIPG (0.53) | TDP1EP300KAT2BKAT5KAT8 | |
| SCHEMBL8076546 | 0.77 | TAAR1 (0.47) | TDP1USP2ALDH1A1HPGDTLR8 | |
| SCHEMBL975133 | 0.75 | LIPG (0.50) | TLR8EP300KAT2BKAT5KAT8 | |
| SCHEMBL248775 | 0.75 | TAAR1 (0.48) | TDP1USP2ALDH1A1HPGDTLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098981-A | POLYORGANOSILOXANE | CHISSO CORPORATION (JP) | 1992-03-24 | — | — | US | disclosed |
| EP-0349920-A2 | Polyorganosiloxane | Chisso Corporation (JP) | 1990-01-10 | — | — | EP | disclosed |