Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | LSS | P48449 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9715905 | 1.00 | CYP1A2 (0.36) | CYP1A2TP53LSSMAPTHTT | |
| SCHEMBL28221245 | 0.86 | CYP1A2 (0.41) | CYP1A2TP53LSSMAPTHTT | |
| SCHEMBL16211186 | 0.84 | LMNA (0.38) | LMNA | |
| SCHEMBL8216620 | 0.80 | CYP1A2 (0.52) | CYP1A2TP53LSSHTTMEN1 | |
| SCHEMBL10486181 | 0.80 | CYP1A2 (0.52) | CYP1A2TP53LSSHTTMEN1 | |
| SCHEMBL10706195 | 0.80 | CYP1A2 (0.52) | CYP1A2TP53LSSHTTMEN1 | |
| SCHEMBL10486024 | 0.80 | CYP1A2 (0.52) | CYP1A2TP53LSSHTTMEN1 | |
| SCHEMBL10485974 | 0.80 | CYP1A2 (0.52) | CYP1A2TP53LSSHTTMEN1 | |
| SCHEMBL8216890 | 0.80 | CYP1A2 (0.52) | CYP1A2TP53LSSHTTMEN1 | |
| SCHEMBL10486095 | 0.80 | CYP1A2 (0.52) | CYP1A2TP53LSSHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0107759-B1 | CYCLOHEXANE DERIVATIVES AND THEIR USE AS COMPONENTS FOR LIQUID CRYSTALS | MERCK PATENT GmbH (DE) | 1992-12-16 | — | — | EP | disclosed |