SCHEMBL9715926

SCHEMBL9715926

O=c1oc2ccc(Br)cc2n1CC#CI

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CBX7 O95931 1/20 0.47
CDYL2 Q8N8U2 1/20 0.47
CDYL Q9Y232 1/20 0.47
CDY1; CDY1B Q9Y6F8 1/20 0.47
SIGMAR1 Q99720 1/20 0.46
NPC1 O15118 1/20 0.44
IDO1 P14902 3/20 0.40
PTGS2 P35354 1/20 0.39
ALDH1A1 P00352 1/20 0.39
CD74 P04233 2/20 0.38
MIF P14174 2/20 0.38
KMO O15229 2/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
ASAH1 Q13510 1/20 0.37
POLB P06746 1/20 0.37
USP2 O75604 1/20 0.37
HPGD P15428 1/20 0.37
TSHR P16473 1/20 0.37
MAPK1 P28482 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9715990 0.89 NPC1 (0.57) CBX7CDYL2CDYLCDY1; CDY1BSIGMAR1
SCHEMBL9715935 0.83 IDO1 (0.61) IDO1KMO
SCHEMBL9716064 0.83 CD74 (0.57) CBX7CDYL2CDYLCDY1; CDY1BIDO1
SCHEMBL9716028 0.83 MIF (0.57) NPC1ALDH1A1CD74MIFMEN1
SCHEMBL9715947 0.81 KMO (0.60) CBX7CDYL2CDYLCDY1; CDY1BIDO1
SCHEMBL9715945 0.80 KMO (0.58) IDO1ALDH1A1CD74MIFKMO
SCHEMBL9715986 0.80 KMO (0.43) IDO1ALDH1A1CD74MIFKMO
SCHEMBL9715940 0.80 KMO (0.58) CBX7CDYL2CDYLCDY1; CDY1BALDH1A1
SCHEMBL536696 0.79 MAPK1 (0.62) IDO1ALDH1A1MIFPOLBUSP2
SCHEMBL9715932 0.79 IDO1 (0.59) CDYL2CDYLCDY1; CDY1BIDO1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5102898-A Halosubstituted alkyne group; fungicides ROHM AND HAAS COMPANY (US) 1992-04-07 US disclosed