SCHEMBL9715932

SCHEMBL9715932

O=c1oc2ccc([N+](=O)[O-])cc2n1CC#CI

nearest known ligand 0.59

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.59
CDYL2 Q8N8U2 1/20 0.47
CDYL Q9Y232 1/20 0.47
CDY1; CDY1B Q9Y6F8 1/20 0.47
ASAH1 Q13510 1/20 0.41
CYP1A2 P05177 1/20 0.41
KMO O15229 2/20 0.38
ALDH1A1 P00352 2/20 0.36
PSMB8 P28062 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9715974 0.90 IDO1 (0.47) IDO1CDYL2CDYLCDY1; CDY1BASAH1
SCHEMBL10507200 0.85 IDO1 (0.63) IDO1CDYL2CDYLCDY1; CDY1BASAH1
SCHEMBL9715935 0.79 IDO1 (0.61) IDO1KMO
SCHEMBL9716028 0.79 MIF (0.57) ALDH1A1
SCHEMBL9715947 0.76 KMO (0.60) IDO1CDYL2CDYLCDY1; CDY1BKMO
SCHEMBL5423077 0.76 IDO1 (0.62) IDO1CDYL2CDYLCDY1; CDY1BASAH1
SCHEMBL9715940 0.75 KMO (0.58) CDYL2CDYLCDY1; CDY1BKMOALDH1A1
SCHEMBL9715986 0.75 KMO (0.43) IDO1KMOALDH1A1
SCHEMBL9715945 0.75 KMO (0.58) IDO1ASAH1CYP1A2KMOALDH1A1
SCHEMBL2061822 0.75 IDO1 (0.64) IDO1CDYL2CDYLCDY1; CDY1BASAH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5102898-A Halosubstituted alkyne group; fungicides ROHM AND HAAS COMPANY (US) 1992-04-07 US disclosed