Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | S100A4 | P26447 | 1/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9715998 | 0.80 | IDO1 (0.35) | IDO1 | |
| SCHEMBL9715954 | 0.79 | POLB (0.39) | MEN1KMT2AIDO1USP2HPGD | |
| SCHEMBL9715956 | 0.79 | IDO1 (0.38) | MEN1KMT2AIDO1USP2HPGD | |
| SCHEMBL9715982 | 0.79 | ALDH1A1 (0.43) | IDO1USP2HPGDTSHRMAPK1 | |
| SCHEMBL9715971 | 0.75 | CYP2A6 (0.41) | HPGDTDP1MIF | |
| SCHEMBL9716043 | 0.73 | CYP2A6 (0.46) | MEN1MAPTKMT2AHPGDTSHR | |
| SCHEMBL536696 | 0.72 | MAPK1 (0.62) | IDO1USP2HPGDTSHRMAPK1 | |
| SCHEMBL9716054 | 0.64 | MIF (0.46) | MEN1MAPTKMT2AIDO1ALDH1A1 | |
| SCHEMBL9716064 | 0.62 | CD74 (0.57) | KMT2AIDO1ALDH1A1MIF | |
| SCHEMBL9716001 | 0.62 | IDO1 (0.35) | IDO1USP2HPGDTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102898-A | Halosubstituted alkyne group; fungicides | ROHM AND HAAS COMPANY (US) | 1992-04-07 | — | — | US | disclosed |