Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 15/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9715996 | 0.89 | KMO (0.54) | KMOIDO1TSHRKMT2ANOS3 | |
| SCHEMBL9715935 | 0.78 | IDO1 (0.61) | KMOIDO1NOS3NOS1NOS2 | |
| SCHEMBL536309 | 0.78 | TDP1 (0.47) | KMONPC1IDO1KMT2ANOS3 | |
| SCHEMBL9715926 | 0.78 | CBX7 (0.47) | KMONPC1IDO1TSHRKMT2A | |
| SCHEMBL9715990 | 0.78 | NPC1 (0.57) | NPC1TSHRKMT2A | |
| SCHEMBL9716054 | 0.77 | MIF (0.46) | KMOIDO1KMT2A | |
| SCHEMBL9715979 | 0.74 | KMO (0.46) | KMOTSHR | |
| SCHEMBL16836516 | 0.73 | KMO (0.80) | KMO | |
| SCHEMBL9715956 | 0.72 | IDO1 (0.38) | NPC1IDO1TSHRKMT2A | |
| SCHEMBL9716064 | 0.72 | CD74 (0.57) | IDO1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102898-A | Halosubstituted alkyne group; fungicides | ROHM AND HAAS COMPANY (US) | 1992-04-07 | — | — | US | disclosed |