Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL1333347 | 0.93 | MEN1 (0.53) | MEN1ALDH1A1TSHRKMT2ACA5A | |
| Sulfuric Acid SCHEMBL3957179 | 0.93 | MEN1 (0.44) | MEN1ALDH1A1TSHRKMT2ACA5A | |
| Sulfuric Acid SCHEMBL41848 | 0.93 | MEN1 (0.53) | MEN1ALDH1A1TSHRKMT2ACA5A | |
| Sulfuric Acid SCHEMBL7949318 | 0.90 | MEN1 (0.50) | MEN1ALDH1A1TSHRKMT2ACA5A | |
| SCHEMBL385808 | 0.89 | MEN1 (0.33) | MEN1ALDH1A1TSHRKMT2ACA2 | |
| Sulfuric Acid SCHEMBL7046606 | 0.86 | MEN1 (0.53) | MEN1ALDH1A1TSHRKMT2ACA5A | |
| Sulfuric Acid SCHEMBL10980849 | 0.86 | MEN1 (0.64) | MEN1ALDH1A1TSHRKMT2ACA5A | |
| SCHEMBL17273487 | 0.85 | MEN1 (0.31) | MEN1ALDH1A1TSHRKMT2A | |
| Ammonia Solution, Strong SCHEMBL6862918 | 0.85 | MEN1 (0.31) | MEN1ALDH1A1TSHRKMT2A | |
| Sulfuric Acid SCHEMBL2808564 | 0.85 | MEN1 (0.31) | MEN1ALDH1A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5080888-A | COMPOSITION AND PROCESS FOR TREATING KERATINIC SUBSTANCES WITH AT LEAST ONE ANIONIC POLYMER AND AT LEAST ONE QUATERNIZED PROTEIN | L'OREAL (FR) | 1992-01-14 | — | — | US | disclosed |
| US-5008105-A | Applying to hair | L'OREAL (FR) | 1991-04-16 | — | — | US | disclosed |
| US-4796646-A | HAIR, SKIN OR NAILS | L'OREAL (FR) | 1989-01-10 | — | — | US | disclosed |