SCHEMBL9716067

SCHEMBL9716067

Cc1cccc(Cl)c1OC(=O)CCS

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.46
L3MBTL1 Q9Y468 3/20 0.43
KMT2A Q03164 3/20 0.41
ATM Q13315 1/20 0.41
MEN1 O00255 1/20 0.41
KDM4E B2RXH2 2/20 0.40
ALDH1A1 P00352 2/20 0.39
POLB P06746 1/20 0.39
TSHR P16473 1/20 0.38
HPGD P15428 1/20 0.37
HSD17B10 Q99714 1/20 0.37
PTPN1 P18031 1/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
RAB9A P51151 1/20 0.36
NLRP3 Q96P20 1/20 0.35
HTT P42858 1/20 0.35
PTPN7 P35236 1/20 0.35
PTPN12 Q05209 1/20 0.35
PTPN22 Q9Y2R2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9716061 0.89 KMT2A (0.46) SMN1; SMN2KMT2AMEN1ALDH1A1TSHR
SCHEMBL3529575 0.82 SMN1; SMN2 (0.50) SMN1; SMN2L3MBTL1KMT2AATMMEN1
Acetic Acid SCHEMBL28940897 0.77 SMN1; SMN2 (0.49) SMN1; SMN2L3MBTL1KMT2AATMMEN1
SCHEMBL9501805 0.76 KDM4E (0.61) SMN1; SMN2L3MBTL1KMT2AKDM4EALDH1A1
SCHEMBL11277533 0.75 KMT2A (0.46) SMN1; SMN2KMT2AMEN1KDM4EALDH1A1
SCHEMBL24636722 0.73 KMT2A (0.47) SMN1; SMN2KMT2AMEN1ALDH1A1TSHR
SCHEMBL28517396 0.73 SMN1; SMN2 (0.59) SMN1; SMN2L3MBTL1KMT2AATMMEN1
SCHEMBL10792928 0.73 SMN1; SMN2 (0.59) SMN1; SMN2L3MBTL1KMT2AATMMEN1
SCHEMBL2058958 0.73 SMN1; SMN2 (0.59) SMN1; SMN2L3MBTL1KMT2AATMMEN1
SCHEMBL30373634 0.72 POLB (0.46) SMN1; SMN2L3MBTL1KMT2AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5147752-A Crosslinked binder FUJI PHOTO FILM CO., LTD. (JP) 1992-09-15 US disclosed