Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.40 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.40 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.40 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716061 | 0.83 | KMT2A (0.46) | KMT2APTPN7PTPN12PTPN22CAMK2A | |
| SCHEMBL11277533 | 0.83 | KMT2A (0.46) | KMT2APTPN7PTPN12PTPN22CAMK2A | |
| SCHEMBL30064393 | 0.81 | KMT2A (0.44) | KMT2APTPN7PTPN12PTPN22CAMK2A | |
| SCHEMBL24120682 | 0.81 | KMT2A (0.44) | KMT2APTPN7PTPN12PTPN22CAMK2A | |
| SCHEMBL4642224 | 0.81 | VCAM1 (0.40) | KMT2AALDH1A1VCAM1TSHRMEN1 | |
| SCHEMBL2898218 | 0.78 | KMT2A (0.48) | KMT2APTPN7PTPN12PTPN22CAMK2A | |
| SCHEMBL4641988 | 0.78 | VCAM1 (0.38) | KMT2AALDH1A1VCAM1TSHRMEN1 | |
| SCHEMBL29152244 | 0.78 | POLM (0.50) | KMT2AALDH1A1SMN1; SMN2MEN1HTT | |
| SCHEMBL30706245 | 0.75 | KMT2A (0.39) | KMT2APTPN7PTPN12PTPN22CAMK2A | |
| SCHEMBL8065623 | 0.74 | KMT2A (0.52) | KMT2APTPN7PTPN12PTPN22CAMK2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022251612-A1 | 2,6-DICHLOROPHENYL ESTER COMPOUNDS AND USE THEREOF | Fusion Pharmaceuticals Inc. (CA) | 2022-12-01 | — | — | WO | disclosed |