Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.34 |
| ▸ | TLR2 | O60603 | 2/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.31 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.31 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.31 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716235 | 0.96 | HTT (0.35) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL9716329 | 0.91 | MEN1 (0.40) | HTTMEN1THRBKMT2AMAPT | |
| Hydrochloric Acid SCHEMBL9716387 | 0.87 | PRKD3 (0.40) | MEN1KMT2A | |
| SCHEMBL9716274 | 0.87 | PLA2G2C (0.33) | USP2PLA2G2CTLR2PLA2G2A | |
| SCHEMBL9716272 | 0.86 | PLA2G2C (0.33) | USP2PLA2G2CTLR2PLA2G2A | |
| Hydrochloric Acid SCHEMBL9716360 | 0.85 | KMT2A (0.39) | HTTMEN1THRBKMT2AMAPT | |
| Hydrochloric Acid SCHEMBL9716466 | 0.83 | PRKD3 (0.45) | MEN1KMT2A | |
| SCHEMBL9716384 | 0.83 | PLA2G2C (0.33) | PLA2G2CTLR2PLA2G2APLA2G10PLA2G1B | |
| Hydrochloric Acid SCHEMBL9716370 | 0.83 | KMT2A (0.41) | HTTMEN1KMT2AMAPTPLA2G1B | |
| Hydrochloric Acid SCHEMBL9716234 | 0.82 | PLA2G4A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5103007-A | Antitumor agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-04-07 | — | — | US | disclosed |
| EP-0378763-A1 | Lipids, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-07-25 | — | — | EP | disclosed |