Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TLR2 | O60603 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 8/20 | 0.31 |
| ▸ | CA2 | P00918 | 8/20 | 0.31 |
| ▸ | CA9 | Q16790 | 7/20 | 0.31 |
| ▸ | CA12 | O43570 | 3/20 | 0.31 |
| ▸ | CA7 | P43166 | 3/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.31 |
| ▸ | CA3 | P07451 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
| ▸ | CA6 | P23280 | 2/20 | 0.31 |
| ▸ | CA5A | P35218 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716274 | 0.97 | PLA2G2C (0.33) | PLA2G2CPLA2G2AKDM4EUSP2ALDH1A1 | |
| SCHEMBL9716384 | 0.93 | PLA2G2C (0.33) | PLA2G2CPLA2G2ATLR2 | |
| SCHEMBL9720198 | 0.89 | PLA2G2A (0.39) | PLA2G2CPLA2G2AKDM4EUSP2ALDH1A1 | |
| SCHEMBL9716235 | 0.88 | HTT (0.35) | PLA2G2CPLA2G2AUSP2TLR2 | |
| SCHEMBL9720263 | 0.87 | PLA2G2A (0.38) | PLA2G2CPLA2G2AKDM4EUSP2ALDH1A1 | |
| SCHEMBL9720221 | 0.87 | PLA2G2A (0.38) | PLA2G2CPLA2G2AKDM4EUSP2ALDH1A1 | |
| SCHEMBL9716254 | 0.86 | HTT (0.35) | PLA2G2CPLA2G2AUSP2TLR2 | |
| Hydrochloric Acid SCHEMBL9716387 | 0.84 | PRKD3 (0.40) | ALDH1A1LMNA | |
| SCHEMBL9716329 | 0.84 | MEN1 (0.40) | PLA2G2CPLA2G2AUSP2ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL9716370 | 0.84 | KMT2A (0.41) | LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5103007-A | Antitumor agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-04-07 | — | — | US | disclosed |
| EP-0378763-A1 | Lipids, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-07-25 | — | — | EP | disclosed |