Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.37 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.37 |
| ▸ | CASR | P41180 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716287 | 0.89 | MEN1 (0.41) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL9716357 | 0.89 | — | — | |
| SCHEMBL9716350 | 0.85 | MEN1 (0.37) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL9716261 | 0.77 | MEN1 (0.40) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL9716257 | 0.77 | MEN1 (0.43) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL9716296 | 0.76 | MAPK1 (0.40) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL9716354 | 0.72 | MEN1 (0.42) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL9716359 | 0.70 | HTT (0.35) | MEN1USP2KMT2A | |
| Hydrochloric Acid SCHEMBL9716279 | 0.69 | GGPS1 (0.35) | MEN1ALDH1A1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL9716340 | 0.69 | MEN1 (0.40) | MEN1USP2ALDH1A1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5103007-A | Antitumor agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-04-07 | — | — | US | disclosed |