⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716361 | 0.90 | MEN1 (0.30) | — | |
| SCHEMBL9716284 | 0.89 | MEN1 (0.37) | — | |
| SCHEMBL9716253 | 0.79 | PLA2G2A (0.31) | — | |
| SCHEMBL9716287 | 0.78 | MEN1 (0.41) | — | |
| SCHEMBL9716309 | 0.78 | — | — | |
| SCHEMBL9716367 | 0.77 | — | — | |
| SCHEMBL9716350 | 0.74 | MEN1 (0.37) | — | |
| SCHEMBL9716258 | 0.73 | PLA2G2A (0.31) | — | |
| SCHEMBL9716240 | 0.72 | PLA2G2A (0.31) | — | |
| SCHEMBL9716228 | 0.72 | PLA2G2C (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5103007-A | Antitumor agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-04-07 | — | — | US | disclosed |