Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716441 | 0.92 | TBXAS1 (0.41) | TBXAS1KMT2AMEN1ALDH1A1HTT | |
| SCHEMBL9720202 | 0.85 | ALDH1A1 (0.48) | TBXAS1KMT2AMEN1ALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL10440073 | 0.84 | ALDH1A1 (0.47) | TBXAS1KMT2AMEN1ALDH1A1HTT | |
| SCHEMBL9716269 | 0.81 | PRKD3 (0.37) | KMT2AMEN1HTTTLR2 | |
| SCHEMBL9716315 | 0.79 | PRKD3 (0.40) | KMT2AMEN1HTTTLR2 | |
| SCHEMBL9716244 | 0.78 | USP2 (0.38) | KMT2AMEN1HTTTLR2 | |
| SCHEMBL9716227 | 0.77 | MEN1 (0.42) | KMT2AMEN1ALDH1A1HTTTLR2 | |
| SCHEMBL9716335 | 0.76 | MEN1 (0.40) | KMT2AMEN1ALDH1A1HTTTLR2 | |
| Hydrochloric Acid SCHEMBL9716276 | 0.76 | PRKD3 (0.47) | KMT2AMEN1ALDH1A1NPSR1LMNA | |
| Hydrochloric Acid SCHEMBL9716239 | 0.75 | PRKD3 (0.46) | KMT2AMEN1ALDH1A1NPSR1TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5103007-A | Antitumor agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-04-07 | — | — | US | disclosed |
| EP-0378763-A1 | Lipids, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-07-25 | — | — | EP | disclosed |