Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR known ✓ | P25105 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9716321 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL9716336 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL9716349 | 0.89 | KMT2A (0.36) | LMNAPTAFRTSHR | |
| Hydrochloric Acid SCHEMBL10385515 | 0.88 | GMNN (0.36) | GMNNUSP2LMNAPTAFRMTOR | |
| Hydrochloric Acid SCHEMBL9716371 | 0.87 | KMT2A (0.34) | LMNAPTAFRTSHR | |
| Hydrochloric Acid SCHEMBL9716386 | 0.85 | HTT (0.43) | — | |
| Hydrochloric Acid SCHEMBL9716259 | 0.85 | KDM4A (0.33) | — | |
| SCHEMBL9716261 | 0.81 | MEN1 (0.40) | USP2LMNATSHR | |
| Hydrochloric Acid SCHEMBL10436596 | 0.81 | KDM4E (0.43) | USP2LMNA | |
| Hydrochloric Acid SCHEMBL10436556 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3014556-A | — | — | None | — | — | JP | disclosed |
| US-5103007-A | Antitumor agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-04-07 | — | — | US | disclosed |
| JP-H0314556-A | LIPID | TAKEDA CHEM IND LTD | 1991-01-23 | — | — | JP | disclosed |
| EP-0378763-A1 | Lipids, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-07-25 | — | — | EP | disclosed |