Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | RAD52 | P43351 | 2/20 | 0.43 |
| ▸ | RGS12 | O14924 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9716386 | 0.84 | HTT (0.43) | HTTBCHEACHE | |
| Hydrochloric Acid SCHEMBL9716349 | 0.83 | KMT2A (0.36) | NPC1HTTSMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9716374 | 0.81 | GMNN (0.34) | LMNAUSP2 | |
| Hydrochloric Acid SCHEMBL9716371 | 0.81 | KMT2A (0.34) | NPC1HTTSMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9716259 | 0.81 | KDM4A (0.33) | — | |
| SCHEMBL9716261 | 0.79 | MEN1 (0.40) | HTTSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL9716257 | 0.79 | MEN1 (0.43) | HTTSMN1; SMN2MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL9716279 | 0.78 | GGPS1 (0.35) | KDM4ENPC1HTTSMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL9716408 | 0.78 | PRKD3 (0.45) | SMN1; SMN2MEN1KMT2ANPSR1LMNA | |
| Hydrochloric Acid SCHEMBL9716322 | 0.77 | PRKD3 (0.44) | SMN1; SMN2MEN1KMT2ANPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0378763-A1 | Lipids, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-07-25 | — | — | EP | disclosed |