⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14880036 | 0.66 | MMP2 (0.38) | — | |
| SCHEMBL14860552 | 0.64 | MMP2 (0.49) | — | |
| SCHEMBL8893930 | 0.62 | — | — | |
| SCHEMBL14879683 | 0.61 | CYP19A1 (0.38) | — | |
| SCHEMBL26526044 | 0.61 | — | — | |
| SCHEMBL24531895 | 0.57 | CHRNB2 (0.31) | — | |
| SCHEMBL4254045 | 0.54 | CA1 (0.39) | — | |
| SCHEMBL25137147 | 0.54 | CA1 (0.39) | — | |
| SCHEMBL24531897 | 0.54 | CYP3A4 (0.35) | — | |
| SCHEMBL754688 | 0.52 | KDM1A (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128486-A | Sulpholenes and processes for their preparation and use | RHONE-POULENC NUTRITION ANIMALE (FR) | 1992-07-07 | — | — | US | disclosed |
| US-5124499-A | Sulpholenes and processes for their preparation and use | RHONE-POULENE NUTRITION ANIMALE (FR) | 1992-06-23 | — | — | US | disclosed |
| US-5082953-A | SULPHOLENES AND PROCESSES FOR THEIR PREPARATION AND USE | RHONE POULENC NUTRITION ANIMALE (FR) | 1992-01-21 | — | — | US | disclosed |
| EP-0446116-A1 | Sulfolenes, process for their preparation and use | RHONE-POULENC NUTRITION ANIMALE (FR) | 1991-09-11 | — | — | EP | disclosed |