Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9255253 | 0.73 | LMNA (0.52) | LMNABLMFNTAPGGT1B | |
| SCHEMBL11690112 | 0.72 | SMN1; SMN2 (0.42) | — | |
| SCHEMBL31567915 | 0.72 | LMNA (0.50) | LMNABLMFNTAPGGT1B | |
| SCHEMBL10258118 | 0.70 | LMNA (0.59) | LMNABLM | |
| SCHEMBL9716465 | 0.70 | TSHR (0.52) | LMNABLMFNTAPGGT1B | |
| SCHEMBL9716256 | 0.69 | ALDH1A1 (0.46) | BLM | |
| SCHEMBL9716460 | 0.69 | LMNA (0.42) | LMNABLMFNTAPGGT1B | |
| SCHEMBL11211348 | 0.67 | — | — | |
| SCHEMBL26189385 | 0.67 | LMNA (0.40) | LMNABLM | |
| SCHEMBL16377876 | 0.66 | LMNA (0.65) | LMNABLMFNTAPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5103007-A | Antitumor agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-04-07 | — | — | US | disclosed |