SCHEMBL9716520

SCHEMBL9716520

CCCCO[Si](CC(CC)OCCCN)(OCCCC)OCCCC

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 5/20 0.41
CYP3A4 P08684 1/20 0.37
TLR2 O60603 4/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30
EPHX1 P07099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12459746 0.75 DNM1 (0.50) DNM1CYP3A4ALDH1A1TSHR
SCHEMBL9716519 0.75 ADRB2 (0.30)
SCHEMBL9861240 0.75 CYP3A4 (0.49) DNM1CYP3A4MEN1KMT2AALDH1A1
SCHEMBL30340413 0.74 CYP3A4 (0.52) DNM1CYP3A4TLR2MEN1KMT2A
SCHEMBL4117174 0.73 DNM1 (0.52) DNM1CYP3A4TLR2MEN1KMT2A
SCHEMBL8953593 0.72 DNM1 (0.50) DNM1CYP3A4TLR2MEN1KMT2A
SCHEMBL5367844 0.72 SMN1; SMN2 (0.47) ALDH1A1TSHR
SCHEMBL23270387 0.72 DNM1 (0.55) DNM1CYP3A4TLR2MEN1KMT2A
SCHEMBL17086768 0.71 CYP3A4 (0.56) DNM1CYP3A4TLR2
SCHEMBL6914579 0.71 CYP3A4 (0.56) DNM1CYP3A4TLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4633002-A Aminofunctional polysiloxane compounds and method of preparation therefor Piskoti, Charles (US) 1986-12-30 US claimed
EP-0274699-B1 A PROCESS FOR PREPARING ACRYLATE-FUNCTIONAL ORGANOPOLYSILOXANE-URETHANE COPOLYMERS WACKER-CHEMIE GMBH (DE) 1992-07-22 EP disclosed
US-4762887-A Process for preparing acrylate-functional organopolysiloxane-urethane copolymers WACKER SILICONES CORPORATION (US) 1988-08-09 US disclosed
EP-0274699-A2 A process for preparing acrylate-functional organopolysiloxane-urethane copolymers WACKER-CHEMIE GMBH (DE) 1988-07-20 EP disclosed
US-4665116-A PYROGENIC SILICA ABRASIVE, AUTOMOBILES TURTLE WAX, INC. (US) 1987-05-12 US disclosed
US-4633002-A Aminofunctional polysiloxane compounds and method of preparation therefor Piskoti, Charles (US) 1986-12-30 US disclosed
EP-0131163-B1 COATING COMPOSITIONS Stauffer-Wacker Silicones Corporation (US) 1986-09-10 EP disclosed
US-4606933-A Acrylate-functional organopolysiloxanes SWS SILICONES CORPORATION (US) 1986-08-19 US disclosed
EP-0095155-B1 PROCESS FOR PREPARING QUATERNARY AMMONIUM-FUNCTIONAL SILICON COMPOUNDS, PRODUCTS PREPARED THEREOF AND USE OF THE SAME Stauffer-Wacker Silicones Corporation (US) 1986-08-06 EP disclosed
US-4584125-A POLYSILOXANE, ORGANIC AMINE OR AMINO-FINCTIONAL ORGANOPOLYSILOXANE, NON-AQUEOUS DISPERSANT, AND FILLER SWS SILICONES CORPORATION (US) 1986-04-22 US disclosed
EP-0048447-A2 Process for preparing silylated organic polymers and their use for treating textile materials SWS Silicones Corporation (US) 1982-03-31 EP disclosed
EP-0044540-A2 Silicone polymer compositions for treating textile materials, processes for preparing the same, a process for treating textile materials and the coated textile material thus treated SWS Silicones Corporation (US) 1982-01-27 EP disclosed
US-4312993-A HYDROPHILIC COATINGS FOR TEXTILES SWS SILICONES CORPORATION (US) 1982-01-26 US disclosed
US-4299879-A COATING WITH A SILYLATED POLYETHER SWS SILICONES CORPORATION (US) 1981-11-10 US disclosed
EP-0026366-A1 Silylated polyethers, processes for preparing the same, compositions for treating textile materials and the coated textile materials thus treated SWS Silicones Corporation (US) 1981-04-08 EP disclosed
US-4247330-A Protective coatings SWS SILICONES CORPORATION (US) 1981-01-27 US disclosed
US-4246029-A Detergent resistant vinyl coatings SWS SILICONES CORPORATION (US) 1981-01-20 US disclosed
US-4230632-A AMINO-FUNCTIONAL SILICONE FLUID SWS SILICONES CORPORATION (US) 1980-10-28 US disclosed
US-4078104-A AMINO-SILANE, POLYSILOXANE COATING SWS SILICONES CORPORATION (US) 1978-03-07 US disclosed
US-3960575-A AMINOFUNCTIONAL SILICON FLUID, HYDROXYL-TERMINATED POLYSILOXANES ANDOR SILICONE RESINS SWS SILICONES CORPORATION (US) 1976-06-01 US disclosed