⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL270119 | 0.87 | HDAC6 (0.39) | — | |
| SCHEMBL28323876 | 0.78 | — | — | |
| SCHEMBL18290964 | 0.78 | — | — | |
| SCHEMBL8089117 | 0.78 | — | — | |
| SCHEMBL23274230 | 0.76 | CA1 (0.46) | — | |
| SCHEMBL28387635 | 0.76 | CA1 (0.46) | — | |
| SCHEMBL8089108 | 0.75 | PSMB11 (0.45) | — | |
| SCHEMBL5791476 | 0.73 | PSMB11 (0.51) | — | |
| SCHEMBL6245505 | 0.73 | CA1 (0.43) | — | |
| SCHEMBL5791472 | 0.73 | PSMB11 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274699-B1 | A PROCESS FOR PREPARING ACRYLATE-FUNCTIONAL ORGANOPOLYSILOXANE-URETHANE COPOLYMERS | WACKER-CHEMIE GMBH (DE) | 1992-07-22 | — | — | EP | disclosed |
| US-4762887-A | Process for preparing acrylate-functional organopolysiloxane-urethane copolymers | WACKER SILICONES CORPORATION (US) | 1988-08-09 | — | — | US | disclosed |
| EP-0274699-A2 | A process for preparing acrylate-functional organopolysiloxane-urethane copolymers | WACKER-CHEMIE GMBH (DE) | 1988-07-20 | — | — | EP | disclosed |