SCHEMBL9716574

SCHEMBL9716574

CCC(C[SiH](OC)OC)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
CCR5 P51681 1/20 0.39
TAAR1 Q96RJ0 2/20 0.39
CYP2D6 P10635 2/20 0.39
CYP1A2 P05177 1/20 0.34
PKM P14618 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
MIF P14174 1/20 0.34
CYP2C9 P11712 4/20 0.34
HKDC1 Q2TB90 1/20 0.33
KMT2A Q03164 1/20 0.33
TRPA1 O75762 1/20 0.33
CTSD P07339 1/20 0.33
CTSE P14091 1/20 0.33
BACE1 P56817 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28435407 0.83 CYP1A2 (0.33) LMNATAAR1CYP2D6CYP1A2PKM
SCHEMBL9716565 0.83 LMNA (0.39) LMNACCR5TAAR1CYP2D6CYP1A2
SCHEMBL28716147 0.79 HTR2A (0.41) LMNATAAR1CYP2D6CYP1A2KMT2A
SCHEMBL3345557 0.77 POLB (0.44) LMNACYP1A2NPSR1KMT2AALDH1A1
SCHEMBL169508 0.76 LMNA (0.56) LMNACCR5TAAR1CYP2D6MIF
SCHEMBL9230452 0.76 TAAR1 (0.48) TAAR1TRPA1ALDH1A1HPGD
SCHEMBL524108 0.76 LMNA (0.43) LMNACCR5TAAR1CYP2D6MIF
SCHEMBL2684234 0.74 SCN4A (0.46)
Ammonia Solution, Strong SCHEMBL1640901 0.74 LMNA (0.54) LMNACCR5TAAR1CYP2D6MIF
SCHEMBL11992984 0.74 LMNA (0.45) LMNACCR5TAAR1CYP2D6CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0282341-B1 PROCESS FOR POLYMERIZATION OF OLEFINS AND POLYMERIZATION CATALYST MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-05-20 EP disclosed
EP-0455313-A1 Process for polymerization of olefins and polymerization catalyst MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-11-06 EP disclosed
US-5028671-A Using coordination catalyst contining magnesium, titanium, halogen compounds with organoaluminum and organosilicon compounds MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-07-02 US disclosed
EP-0282341-A1 Process for polymerization of olefins and polymerization catalyst MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-09-14 EP disclosed