Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.49 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 5/20 | 0.44 |
| ▸ | CTSH | P09668 | 4/20 | 0.44 |
| ▸ | CTSK | P43235 | 4/20 | 0.44 |
| ▸ | CTSL | P07711 | 3/20 | 0.44 |
| ▸ | CTSS | P25774 | 3/20 | 0.44 |
| ▸ | CTSF | Q9UBX1 | 2/20 | 0.44 |
| ▸ | CTSV | O60911 | 1/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716584 | 1.00 | FOLH1 (0.49) | FOLH1PLGCTSBCTSHCTSK | |
| SCHEMBL9716721 | 1.00 | FOLH1 (0.49) | FOLH1PLGCTSBCTSHCTSK | |
| SCHEMBL9716612 | 0.95 | FOLH1 (0.55) | FOLH1PLGCTSBCTSHCTSK | |
| SCHEMBL8510233 | 0.95 | FOLH1 (0.55) | FOLH1PLGCTSBCTSHCTSK | |
| SCHEMBL9716645 | 0.92 | CTSB (0.50) | CTSBCTSHCTSKCTSLCTSS | |
| SCHEMBL9716652 | 0.92 | CTSB (0.50) | CTSBCTSHCTSKCTSLCTSS | |
| SCHEMBL9716657 | 0.92 | CTSB (0.50) | CTSBCTSHCTSKCTSLCTSS | |
| SCHEMBL7890166 | 0.87 | CPB2 (0.55) | CTSBCTSHCTSKCTSLCTSS | |
| SCHEMBL9716618 | 0.87 | CPB2 (0.55) | CTSBCTSHCTSKCTSLCTSS | |
| SCHEMBL8057049 | 0.83 | FOLH1 (0.46) | FOLH1CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178911-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1992-01-22 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0178911-A2 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1986-04-23 | — | — | EP | disclosed |