Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.47 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 6/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 2/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716663 | 1.00 | FOLH1 (0.47) | FOLH1SLC6A5NOD1CYP1A2CPB2 | |
| SCHEMBL9716671 | 1.00 | FOLH1 (0.47) | FOLH1SLC6A5NOD1CYP1A2CPB2 | |
| Hydrochloric Acid SCHEMBL28028607 | 0.98 | FOLH1 (0.46) | FOLH1SLC6A5NOD1CYP1A2CPB2 | |
| SCHEMBL9716676 | 0.95 | FOLH1 (0.54) | FOLH1SLC6A5NOD1CYP1A2CPB2 | |
| SCHEMBL9716669 | 0.95 | FOLH1 (0.54) | FOLH1SLC6A5NOD1CYP1A2CPB2 | |
| Hydrochloric Acid SCHEMBL28265302 | 0.94 | FOLH1 (0.53) | FOLH1SLC6A5NOD1CPB2TGM2 | |
| SCHEMBL9832048 | 0.86 | NOD1 (0.49) | NOD1TGM2SIRT2SIRT1 | |
| SCHEMBL9832042 | 0.86 | NOD1 (0.49) | NOD1TGM2SIRT2SIRT1 | |
| SCHEMBL6688677 | 0.86 | NOD1 (0.47) | FOLH1SLC6A5NOD1ITGB3ITGA2B | |
| SCHEMBL9716662 | 0.86 | NOD1 (0.47) | FOLH1SLC6A5NOD1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178911-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1992-01-22 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0178911-A2 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1986-04-23 | — | — | EP | disclosed |