Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 7/20 | 0.49 |
| ▸ | CTSS | P25774 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 3/20 | 0.44 |
| ▸ | TGM2 | P21980 | 2/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | ECE1 | P42892 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9832048 | 1.00 | NOD1 (0.49) | NOD1CTSSCTSLCTSKTGM2 | |
| SCHEMBL6269749 | 0.95 | NOD1 (0.51) | NOD1TGM2SIRT2SIRT1MAPK1 | |
| SCHEMBL1858630 | 0.89 | FPR2 (0.43) | NOD1CTSSCTSKTGM2SIRT2 | |
| SCHEMBL7382637 | 0.88 | NOD1 (0.48) | NOD1CTSSCTSLCTSKTGM2 | |
| SCHEMBL9830451 | 0.88 | NOD1 (0.47) | NOD1CTSSCTSLCTSKTGM2 | |
| SCHEMBL9830456 | 0.88 | NOD1 (0.47) | NOD1CTSSCTSLCTSKTGM2 | |
| SCHEMBL1077922 | 0.88 | NOD1 (0.48) | NOD1CTSSCTSLCTSKTGM2 | |
| Hydrochloric Acid SCHEMBL27527505 | 0.87 | FPR2 (0.42) | NOD1CTSSCTSKTGM2SIRT2 | |
| SCHEMBL9716671 | 0.86 | FOLH1 (0.47) | NOD1TGM2SIRT2SIRT1 | |
| SCHEMBL9831687 | 0.86 | FOLH1 (0.47) | NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |