SCHEMBL9716679

SCHEMBL9716679

NCCCC(C(=O)O)N(C(=O)c1ccccc1)C(=O)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ADRA2C P18825 1/20 0.50
F2 P00734 1/20 0.45
HTR2A P28223 1/20 0.42
HRH1 P35367 1/20 0.42
TRPM8 Q7Z2W7 1/20 0.37
MMP2 P08253 1/20 0.36
MMP9 P14780 1/20 0.36
CPB2 Q96IY4 1/20 0.36
ALPI P09923 1/20 0.36
PKM P14618 1/20 0.36
PTGS1 P23219 1/20 0.36
XIAP P98170 1/20 0.36
SLC7A5 Q01650 1/20 0.36
TSHR P16473 1/20 0.36
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.36
EPOR P19235 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15484293 1.00 ADRA2C (0.50) ADRA2CF2HTR2AHRH1TRPM8
SCHEMBL9716684 1.00 ADRA2C (0.50) ADRA2CF2HTR2AHRH1TRPM8
SCHEMBL1387992 0.95 F2 (0.50) ADRA2CF2HTR2AHRH1TRPM8
SCHEMBL9716623 0.95 F2 (0.50) ADRA2CF2HTR2AHRH1TRPM8
SCHEMBL7321837 0.95 F2 (0.50) ADRA2CF2HTR2AHRH1TRPM8
SCHEMBL10898039 0.92 ADRA2C (0.43) ADRA2CF2HTR2AHRH1TRPM8
SCHEMBL9716633 0.88 ADRA2C (0.38) ADRA2CF2HTR2AHRH1CPB2
SCHEMBL9716649 0.88 ADRA2C (0.38) ADRA2CF2HTR2AHRH1CPB2
SCHEMBL9716674 0.88 SLC7A5 (0.39) ADRA2CF2CPB2PKMSLC7A5
SCHEMBL9716685 0.88 SLC7A5 (0.39) ADRA2CF2CPB2PKMSLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9434924-B2 Cell culture method and cell culture kit NIPRO CORPORATION (JP) 2016-09-06 US claimed
EP-0178911-B1 COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC SANKYO COMPANY LIMITED (JP) 1992-01-22 EP claimed
EP-0178911-A2 Composition containing a penem or carbapenem antibiotic SANKYO COMPANY LIMITED (JP) 1986-04-23 EP claimed
EP-2700707-B1 CELL CULTURE METHOD AND CELL CULTURE KIT NIPRO CORP (JP) 2018-06-06 EP disclosed
US-20140087465-A1 CELL CULTURE METHOD AND CELL CULTURE KIT NIPRO CORPORATION (JP) 2014-03-27 US disclosed
EP-2700707-A1 CELL CULTURE METHOD AND CELL CULTURE KIT Nipro Corporation (JP) 2014-02-26 EP disclosed
EP-0178911-B1 COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC SANKYO COMPANY LIMITED (JP) 1992-01-22 EP disclosed
EP-0178911-A2 Composition containing a penem or carbapenem antibiotic SANKYO COMPANY LIMITED (JP) 1986-04-23 EP disclosed